Home Safety Alert Subcutaneous Vasculitis Associated With Metformin & Vildagliptin

Subcutaneous Vasculitis Associated With Metformin & Vildagliptin

Subcutaneous Vasculitis Associated With Metformin & Vildagliptin

Subcutaneous vasculitis is a condition characterized by inflammation of the walls of the blood vessels. This may compromise or lead to destruction of affected blood vessels resulting in hemorrhagic and ischemic events. Subcutaneous vasculitis is caused by several factors which include primary factors such as idiopathic cutaneous leukocytoclastic angiitis or
Wegener granulomatosis and secondary disorders (connective tissue disease, infections, or adverse drug eruption-associated vasculitis).1,2 Some of the other medicines like beta lactam antibiotics, sulphonamides, non-steroidal anti-inflammatory drugs, retinoids, thiazides, insulin, and quinolone group antibiotics are also associated with subcutaneous vasculitis.

Most vaccines are safe and well tolerated. However, if you experience any discomfort after vaccination, seek immediate medical attention and ask your healthcare provider to report the event to BoMRA

Botswana Medicines Regulatory Authority
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