Home Safety Alert Bedaquiline-containing regimenscardiac adverse events

Bedaquiline-containing regimenscardiac adverse events

Bedaquiline-containing regimenscardiac adverse events

Bedaquiline is an antimycobacterial drug used for the treatment of pulmonary multidrug resistant tuberculosis.
Bedaquiline inhibits adenosine 5′-triphosphate (ATP) synthesis, a process that is crucial to the growth of mycobacterium
and to its survival in its non-growing dormant state. Bedaquiline is recommended for the treatment of pulmonary
Multidrug Resistant Tuberculosis (MDR-TB) and Rifampicin Resistant-Tuberculosis medicines (RR-TB) by world health
organization. Bedaquiline is used in Botswana for management of MDR-TB and RR-TB.

Most vaccines are safe and well tolerated. However, if you experience any discomfort after vaccination, seek immediate medical attention and ask your healthcare provider to report the event to BoMRA

Botswana Medicines Regulatory Authority
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